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Plasma components (eg, fresh frozen plasma, cryoprecipitate or cryodepleted plasma) for transfusion should be compatible with the ABO group of the recipient, to avoid potential haemolysis caused by donor anti-A or anti-B. Matching for the Rh(D) type is not necessary.
| Compatible ABO Groups for Plasma Transfusions | |||||
| Patient’s ABO blood group | ABO blood group of plasma for transfusion | Unit ABO Group* | |||
| O | A | B | AB | ||
| Unknown | AB (if required urgently) | 1 | |||
| O | O or A or B or AB | 1 | 2 | 3 | 4 |
| A | A or AB | 1 | 2 | ||
| B | B or AB | 1 | 2 | ||
| AB | AB (A if AB unobtainable) | 2 | 1 | ||
| Note: *1 = primary choice; 2 to 4 = second, third and last choice where supply of ABO identical blood is limited; Individual plasma units of different blood groups must not be pooled. | |||||
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