Specific factors to consider when using red cells

Besides the haemoglobin level, patient factors, signs and symptoms of hypoxia, ongoing blood loss, the risk to the patient of anaemia with coexisting conditions, and transfusion risk should be considered when using red cells. 

  • Patient’s cardiopulmonary reserve — if pulmonary function is not normal, it may be necessary to consider transfusing at a higher threshold.

  • Volume of blood loss — clinical assessment should attempt to quantify the volume of blood loss before, during and after surgery, to ensure maintenance of normal blood volume.

  • Oxygen consumption — this may be affected by a number of factors including fever, anaesthesia and shivering; if increased then the patient’s need for red blood cell transfusion could be higher.

  • Atherosclerotic disease — critical arterial stenosis to major organs, particularly the heart, may modify indications for the use of red blood cells.

For further details, consult the Clinical Practice Guidelines on the Use of Blood Components(1).

 

Reference

  1. National Health and Medical Research Council & Australasian Society of Blood Transfusion. Clinical Practice Guidelines on the Use of Blood Components. Commonwealth of Australia, October 2002.