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Acute DIC is a medical emergency and is always aimed towards eliminating the precipitating trigger (if possible) and treating any associated issues, such as infection or acidosis. Specialist advice is recommended.
In the presence of widespread bleeding, specific replacement with blood component therapy should be given.
|Blood Component Therapy in Disseminated Intravascular Coagulation|
|Blood component||Indication in DIC|
|Fresh frozen plasma||
Following initial replacement therapy, laboratory tests should be repeated. Any further treatment is guided by both clinical and laboratory responses.
Prothrombinex-VF is contraindicated as it may potentiate existing thrombotic tendency, which is a feature of patients with DIC. The role of heparin is controversial.