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Arguments over the best type of fluid for volume resuscitation have been ongoing for more than 30 years.
Data from clinical trials suggests no therapeutic advantage for either crystalloids or colloids. Physiologically balanced crystalloid and colloid solutions may improve clinical outcomes when compared with saline-based fluids.(1)
|Characteristics of Different Types of Plasma Volume Replacement Fluids|
|Plasma Volume Replacement Fluid||Characteristics||Indications|
Normal saline (sodium chloride 0.9%)
Used to replace abnormal losses of blood, plasma or other extracellular fluids principally in:
Gelatin (urea linked), eg Haemacel Gelatin (succinylated), Gelofusine Dextran 70 (6%)
Dextran 60 (3%)
Hydroxyethyl starch (N/A in Australia)
Albumin solutions, eg Albumex 4
Replacement of blood volume, however have not been shown to be superior to crystalloids in resuscitation.
May cause volume overload.
4% Glucose in 0.18% sodium chloride
Used to replace normal physiological losses through the skin, lung, faeces and urine.
Do not use to treat hypovolaemia unless there is no alternative.