This site complies with the HONcode standard for trustworthy health information: verify here.
The human neutrophil alloantigens (HNA) system currently includes 7 antigens assigned to 5 antigen groups, as shown in the table below.
Neutrophil-specific antibodies are implicated in:
Neonatal alloimmune neutropenia
Autoimmune neutropenia
The detection of neutrophil antibodies requires specialised testing.
|
Human Neutrophil Antigen (HNA) Systems(1) |
||||||
|
Antigen group |
Antigen |
Acronym |
Frequency % |
|||
| White | Asians(a) |
Africans(b) |
Amerindians(c) |
|||
|
HNA-1 |
HNA-1a |
NA1 |
57–62 |
88–91 |
46–66 |
83–91 |
|
|
HNA-1b |
NA2 |
88–89 |
51–54 |
78–84 |
36–80 |
|
|
HNA-1c |
SH |
5 |
<1 |
23–31 |
0–1 |
|
|
HNA-1 null |
|
0, 15 |
<1 |
4 |
<1 |
|
HNA-2 |
HNA-2 |
NB1 |
87–97 |
89–99 |
98 |
|
|
HNA-3 |
HNA-3a |
5b |
89–96 |
|
|
|
|
HNA-4 |
HNA-4a |
Mart |
99 |
|
|
>99 |
|
HNA-5 |
HNA-5a |
Ond |
86–92 |
81 |
88 |
79–97 |
|
Notes: (a) Chinese, Japanese, Koreans or Taiwanese; (b) African and American blacks; (c) North and South American Indians |
||||||
This site complies with the HONcode standard for trustworthy health information: verify here.