Alloantibodies causing haemolytic transfusion reactions or haemolytic disease in the fetus and newborn are dependent on the frequency with which alloantigens and alloantibodies occur.
| Major Blood Group Phenotypes and their Frequencies (1–3) | |||||||
| No | Blood Group System [Symbol] | Phenotype | % Frequency | No | Blood Group System [Symbol] | Phenotype | % Frequency |
|
001 |
ABO [ABO] |
A1 |
29.7 |
014 | Dombrock [DO]** | Do(a+b–) | 18 |
|
|
|
A2 |
9.3 |
Do(a–b+) | 33 | ||
|
|
|
B |
11.4 |
Do(a+b+) | 49 | ||
|
|
|
O |
46.1 |
Gy(a–) | Rare | ||
|
|
|
A1B |
2.3 |
015 | Colton | Co(a+b–) | 92.0 |
|
|
|
A2B |
1.2 |
Co(a–b+) | 0.2 | ||
|
002 |
MNS [MNS] |
MMSS |
6.0 |
Co(a+b+) | 7.8 | ||
|
|
|
MMss |
9.1 |
016 | Landsteiner-Wiener [LW]** | LW(a+b–) | 97 |
|
|
|
MMSs |
14.4 |
LW(a–b+) | Rare | ||
|
|
|
MNSS |
3.0 |
LW(a+b+) | 3 | ||
|
|
|
MNss |
23.3 |
017 |
Chido/Rogers [CH/RG]** | Chido phenotype | |
|
|
|
MNSs |
22.7 |
CH/RG: 1,2,3 | 88.2 | ||
|
|
|
NNSS |
0.4 |
CH/RG: 1,–2,3 | 4.9 | ||
|
|
|
NNss |
15.6 |
CH/RG: 1,2,–3 | 3.1 | ||
|
|
|
NNSs |
5.5 |
CH/RG: –1,–2,–3 | 3.8 | ||
|
003 |
P [P] |
P1+ |
74.8 |
CH/RG: –1,2,-3 | Rare | ||
|
|
|
P1– |
25.2 |
CH/RG: 1,–2,–3 | Rare | ||
|
004 |
Rh [RH] |
Rodgers phenotype | |||||
|
005 |
Lutheran [LU] |
Lu(a+b–) |
0.2 |
CH/RG: 11,12 | 95 | ||
|
|
|
Lu(a–b+) |
92.3 |
CH/RG: 11,–12 | 3 | ||
|
|
|
Lu(a+b+) |
7.5 |
CH/RG: –11,–12 | 2 | ||
|
|
|
Lu(a–b–) |
Rare |
018 | H [H] | H | High incidence |
|
006 |
Kell [KEL] |
K– k+ |
90.9 |
019 | Kx [XK] | Kx | High incidence |
|
|
|
K+ k– |
0.4 |
020 | Gerbich [GE]** | Ge:2,3,4 | >99.9 |
|
|
|
K+ k+ |
8.7 |
Ge:–2,3,4 (Yus type) | Rare | ||
|
|
|
Kp(a+b–) |
<0.1 |
Ge:–2,–3,4 (Gerbich type) | Rare | ||
|
|
|
Kp(a–b+) |
97.8 |
Ge:–2,–3,–4 (Leach) | Rare | ||
|
|
|
Kp(a+b+) |
2.2 |
021 | Cromer [CROM] | Cra, Tca, Dra, Esa | High Incidence |
|
007 |
Lewis [LE] |
Le(a+b–) |
22.4 |
Tcb, Tcc, WESa | Low incidence | ||
|
|
|
Le(a–b+) |
72.3 |
022 | Knops [KN]** | Kn(a+b–) | 94.5 |
|
|
|
Le(a–b–) |
5.3 |
Kn(a–b+) | 1 | ||
|
008 |
Duffy [FY] |
Fy(a+b–) |
19.7 |
Kn(a+b+) | 4.5 | ||
|
|
|
Fy(a–b+) |
32.7 |
McC(a+) | 98 | ||
|
|
|
Fy(a+b+) |
47.6 |
Sl(a+) | 98 | ||
|
009 |
Kidd [JK] |
Jk(a+b–) |
26.3 |
Yk(a+) | 92 | ||
|
|
|
Jk(a–b+) |
23.6 |
023 | Indian [IN]** | In(a+b–) | Rare |
|
|
|
Jk(a+b+) |
50.1 |
In(a–b+) | 99.9 | ||
|
010 |
Diego [DI]** |
Di(a+b–) |
<0.01 |
In(a+b+) | <0.1 | ||
|
|
|
Di(a-b+) |
>99.9 |
024 |
Ok [OK]** | Ok(a+) | 100 |
|
|
|
Di(a+b+) |
<0.1 |
Ok(a–) | Rare | ||
|
|
|
Wr(a+) |
<0.1 |
025 |
Raph [RAPH] | MER2 | |
|
|
|
Wr(b+) |
High incidence |
026 |
John Milton Hagen [JMH] | JMH | High incidence |
|
011 |
Yt [YT]** |
Yt(a+b–) |
91.9 |
027 | I [I] | I | High incidence |
|
|
|
Yt(a–b+) |
0.3 |
028 |
Globoside [GLOB] | P | High incidence |
|
|
|
Yt(a+b+) |
7.8 |
029 | Gill [GIL] | GIL | High incidence |
|
012 |
Xg [XG]** |
Xg(a+) |
Male 65.6 Female 88.7 |
Antigen Collections** |
Csa / Csb Vel / ABTI
|
95 / 34 Both >99
|
|
|
|
|
Xg(a–) |
Male 34.4 Female 11.3 |
Low incidence antigens (700 series) | By, Chra, Bi, Bxa, Pta, Rea etc. | <1 | |
|
013 |
Scianna [SC]** |
Sc:1,–2 |
99 |
High incidence antigens (901 series) | Lan, Ata, Jra, AnWj, Sda, Duclos etc. | >90 | |
|
|
|
Sc:–1,2 |
Rare |
||||
|
|
|
Sc:1,2 |
1 |
||||
|
|
|
Sc:1,–2,Rd+ |
Rare |
||||
|
|
|
Sc:1,2,Rd+ |
Rare |
||||
| Note: Unless indicated, frequencies are based on blood group statistics of Australian blood donors; ** Frequency is based on Caucasian population. | |||||||
