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It contains most clotting factors in similar amounts to fresh frozen plasma but is deficient in factor VIII, fibrinogen, von Willebrand factor (the high molecular weight multimers are more thoroughly removed than the smaller multimers), factor XIII and fibronectin.
Cryodepleted plasma derived from whole blood is available in all ABO groups. You must contact the Blood Service if apheresis cryodepleted plasma is available.
There is no modification available for cryodepleted plasma.
The volume of cryodepleted plasma derived from whole blood is between 215–280 mL.
Cryodepleted plasma apheresis is 550 ml ± 10% in volume.