Cryoprecipitate
This component, either derived from whole blood or collected via apheresis, is prepared by thawing fresh frozen plasma between 1–6 ˚C and recovering the precipitate. The cold-insoluble precipitate is refrozen.
One unit of cryoprecipitate apheresis is approximately equivalent to 2 units of cryoprecipitate derived from whole blood.
It contains most of the factor VIII, fibrinogen, factor XIII, von Willebrand factor and fibronectin from fresh frozen plasma.
Cryoprecipitate derived from whole blood is available in all ABO groups.
You must contact the Blood Service if cryoprecipitate collected through apheresis is available.
There is no modification available for cryoprecipitate.
| Specifications of Cryoprecipitate | ||
| Cryoprecipitate | Cryoprecipitate apheresis | |
| Volume | 30–40 mL | 60 mL ± 10% |
| Fibrinogen | > 140 mg/unit | > 140 mg/unit |
| Factor VIIIc | > 70 IU/unit | > 70 IU/unit |
| Von Willebrand factor | > 100 IU/unit | > 100 IU/unit |
